In this video, Ira Espuny-Camacho and Pierre Vanderhaeghen describe how human pluripotent stem cells can be turned into cortical pyramidal neurons, mimicking key aspects of human corticogenesis. Most ...
Control of Glutamate Receptor Function in the Hippocampus
The hippocampus plays a pivotal role for learning and memory. In this video we show how two proteins—CKAMP44 and TARP gamma-8—that bind to AMPA receptors control information flow into the hippocampus....
Mitochondrial links to genomic instability in aging
Mitochondrial links to genomic instability in aging - Understanding why our genomes become more prone to mutations as we age is a key goal of ageing and cancer research. Dr. Dan Gottschling and his co...
Transposon Silencing of Small RNAs - Dr. Thomas Tuschl discusses the context for the work on small RNA profiling during Drosophila development and elaborates on our current understanding of some of th...
Human Mutation - Kakkhee Yeung "Transdifferentiation of Human Dermal Fibroblasts to Smooth Muscle-Like Cells to Study the Effect of MYH11 and ACTA2 Mutations in Aortic Aneurysms"...
Memory Enhancement by Targeting NR2B Cell Surface Regulation
Many neurological disorders, such as Alzheimer's disease, are characterized by learning and memory deficits, for which cognitive enhancement is considered a valid treatment strategy. Plattner and coll...
In A Flash: Firefly Communication - Fireflies communicate with a "language of light" that scientists still don't completely understand. James Lloyd and Marc Branham of the University of Flor...
Assembly and budding of a virus from a membrane microdomain
Assembly and Budding of a Virus from a Membrane Microdomain - Viruses have an outer protein shell (called a capsid) that surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an addit...
Potentiation in Motor Learning - Traditionally, long-term depression at the parallel fiber to Purkinje cell synapse has been considered to be the process underlying cerebellar motor learning. In this ...
Atomic Views of Viral Priming with Cryo-EM - Nonenveloped viruses must transform from a dormant state to a primed state for cell membrane penetration. Watch and listen as Hong Zhou takes you on a brie...
How to Inflame Cancer Growth / Cell, July 13, 2017 (Vol. 170, Issue 2)
How to Inflame Cancer Growth. Cancer cells are surrounded by normal cells like fibroblasts and immune cells, but can they be corrupted to promote growth of a tumor? In this video abstract, Andy Minn a...
Extrinsic Cues in Neuronal Polarity - Is the site of axon emergence determined by intrinsic neuronal polarity or the local environment? Bill Harris and colleagues have found that laminin at the basal ...
