CONVERSATIONS IN THE BRAIN: How neural progenitor cells control their own fate
Neurogenesis relies on a delicate balance between progenitor maintenance and neuronal production. Oscar Marin and colleagues find that the Robo1 and Robo2 receptors and their Slit protein ligands, kno...
Retinal Direction Selectivity Is Reversed by Visual Stimulation
A classic neural computation is that of detecting the direction of motion of an object within the visual scene. Direction-selective cells in the retina respond strongly to an image moving in the prefe...
This video abstract accompanies the article The resilience of the forest field layer to anthropogenic disturbances depends on site productivity by Kaupo Kohv, Martin Zobel, Jaan Liira, published in Ca...
Helicases Find Their Way - Hexameric helicases unwind DNA or RNA duplexes using ATP as an energy source. Watch and listen as James Berger and Nathan Thomsen take you on a brief, personally guided tou...
Synapses are formed with high degree of specificity in our brain. In this VIDEO, Kang Shen and Kota Mizumoto describes "synaptic tiling" as a way to precisely organize the subcellular locati...
p53's Hit Men - p53 both activates and represses gene expression to defend against tumorigenesis. Watch and listen as John Rinn takes you on a brief, personally guided tour of his lab's findings that ...
Uncovering Diverse Navigational Codes in Entorhinal Cortex
Uncovering Diverse Navigational Codes in Entorhinal Cortex. Cells in medial entorhinal cortex encode position, head direction, and running speed in more complex ways than previously thought. Applicati...
Shedding Light on HCN Channel Gating - The mechanism underlying HCN channel activation, including the relative contributions of membrane voltage and the ligand cAMP, is unknown. Klaus Benndorf and col...
In this video, Tsai and colleagues summarize the current state of knowledge about how DNA damage and changes to the DNA damage response in neurons might underlie neurodegenerative disorders. For more ...
Obtaining a clear picture of the proteins that interact with the Huntingtin protein will provide clues for the development of Huntington's disease therapies. In this study, William Yang and colleagues...