External genital anatomy evolves rapidly and is remarkably diverse among animals that reproduce by internal fertilization. One of the most intriguing evolutionary transitions is the reduction and loss...
Bioluminescent millipedes - Bioluminescence is the ability of an organism to generate its own light. Numerous functions have been proposed for the 40 or more independent origins of bioluminescence, fo...
Julie Blander and colleagues explain how MHC-I stored in the endosomal recycling compartment of dendritic cells is delivered to phagosomes for cross-presentation through TLR signaling-dependent mechan...
Gene Discovery in Mendelian Brain Disorders - A Center for Mendelian Genomics gene discovery study is presented that utilizes genomic approaches, which detect rare variant—single nucleotide variants (...
Poop and Paddle: An Eco-Friendly Floating Toilet - This toilet floats. It's an outhouse and sewage-treatment plant in one, processing human waste through a "constructed wetlands." Adam Katzm...
Fruit chemistry alters animal behavior. This study shows the role of secondary metabolites in ripe fruits in shaping plant-animal interactions, not only by directly deterring seed predators but also b...
Shedding Light on HCN Channel Gating - The mechanism underlying HCN channel activation, including the relative contributions of membrane voltage and the ligand cAMP, is unknown. Klaus Benndorf and col...
Octopamine Regulation of Sleep - An understanding of sleep requires identification of the circuits that mediate the action of specific sleep:wake-regulating molecules. Watch and listen as Amanda Crock...
Causal Role of Theta Oscillations in Auditory Working Memory
Causal Role of Theta Oscillations in Auditory Working Memory. This study shows that driving brain oscillations with rhythmic stimulation can specifically improve auditory working memory performance an...
Hearing in a Jumping Spider/ Curr. Biol., Oct. 13, 2016 (Vol. 26, Issue 21)
Hearing in a Jumping Spider/ Curr. Biol., Oct. 13, 2016 (Vol. 26, Issue 21) - Jumping spiders (Salticidae) are famous for their visually driven behaviors [ 1 ]. Here, however, we present behavioral an...
Local Translation Regulates Trigeminal Patterning - Retrograde signaling mechanisms contribute to the specification of neuronal identity via regulation of gene transcription in the developing nervous ...
F-BAR proteins: Coordinating the effects of actin and dynamin on endocytosis
F-BAR proteins: Coordinating the effects of actin and dynamin on endocytosis - Pietro De Camilli discusses how his group came to define the F-BAR domain and its role in endocytosis, and where subseque...
Human and Dog Brains Both Have Dedicated "Voice Areas"
The video presents the first study to compare brain function between humans and any nonprimate animal. Scientists at MTA-ELTE Comparative Ethology Research Group in Hungary found that dogs and humans ...
Imaging Clock Oscillations in the Mouse Embryo - The periodic, anteriorly traveling waves of cyclic gene expression can be seen in the presomitic mesoderm (PSM) of a transgenic mouse embryo. The trans...
The Bacterial Effector VopL Organizes Actin into Filament-like Structures
Michael Rosen and colleagues find that a pathogen effector protein assembles actin filaments through the collaborative action of an organizing domain that templates filament structure through both low...