Control of Cerebrovascular Networks Formation by Neural Activity
This video summarizes a study from Dr. Chenghua Gu's laboratory at Harvard Medical School, which demonstrates that sensory-related neural activity influences the formation of brain vascular networks d...
Sortilin Link to Dementia Pathophysiology - Mutation of the gene for PGRN causes Fronto-Temporal Lobar Degeneration but the mechanistic link between reduced PRGN levels and neurodegeneration is unknow...
Watching Inhibitory Synapses Remodel - By simultaneously monitoring in vivo synapse and dendritic spine dynamics in adult mammalian cortical pyramidal cells, Elly Nedivi and colleagues provide new ins...
Research Discoveries in Schizophrenia - Meet the Scientists Webinar
Masseck et al. describe two new optogenetic tools to selectively activate the Gi/o pathway in anxiety circuitries. In the future these new tools might be applicable for new therapeutic strategies. For...
Dorsal Striatal Neural Clusters Encode Locomotion - An influential striatal model postulates that neural activities in the striatal direct and indirect pathways promote and inhibit movement, respectiv...
Extracellular Fuel for Metastasis - Cancer cells enhance their ability to metastasize by producing phospho-creatine, a metabolite that fuels metastatic survival, in the extracellular space. This proce...
Baron Chanda and colleagues describe the principles for temperature gating in ion channels and how temperature-insensitive channels can be made cold or heat responsive....
Gaining mechanistic insight into age-related obesity can provide clues to developing therapeutic approaches for treating this condition. In this study, Lily Jan and colleagues discover that an increas...
