Orchestrated amplification and differentiation of intermediate progenitors governs the evolutionary expansion of the cerebral cortex. Fang et al. report that Axin serves as a master scaffold that dete...
Mutations in GlialCAM Can Cause the Leukodystrophy MLC
Mutations in GlialCAM Can Cause the Leukodystrophy MLC - Mutations in the cell adhesion molecule GlialCAM can cause the leukodystrophy MLC. Raul Estevez and colleagues find that GlialCAM acts as an au...
Pericyte Control of Neurovascular Function - Pericytes are known to play a key role in the development of cerebral microcirculation but their function in the adult brain and during aging is not clear....
Bidirectional Transcription and Antisense Repression of ataxin-7
Bidirectional Transcription and Antisense Repression of ataxin-7 - CAG repeat expansions in the ataxin-7 gene cause the neurodegenerative disorder SCA7. Al La Spada and colleagues have discovered tha...
A Sticky Wicket: Opposing Functions of p120-Catenin in Development and Cancer
A Sticky Wicket: Opposing Functions of p120-Catenin in Development and Cancer - Albert Reynolds discusses how his group came to examine the role of p120-catenin in the mouse salivary gland and the imp...
Jeannie Lee and colleagues show that the X-linked Jpx noncoding RNA antagonizes the autosomally encoded CTCF transcription factor by titrating it away from the Xist promoter during X chromosome inacti...
Human Mutation - Brianne Kirkpatrick and colleagues
Authors, Brianne Kirkpatrick and colleagues, on their published paper in Human Mutation entitled "GenomeConnect: Matchmaking Between Patients, Clinical Laboratories, and Researchers to Improve Ge...
