Leptin nixes appetite through serotonin - Leptin is a molecule that acts in the brain to regulate appetite, energy expenditure and bone mass. Gerard Karsenty and his colleagues explain how they disco...
Exploring Astrocyte Diversity in Neural Circuits. Chai, Díaz-Castro et al. briefly highlight methods used to explore astrocytes in the hippocampus and striatum. The data show that astrocytes are disti...
Atypical female courtship, including enhanced genital biting, characterizes a novel stock of laboratory mice. This heritable anomaly appeared together with ectopic Hoxd gene expression in the adult br...
Ocean 180 -- Innocence by Viral Tagging. Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in...
Unraveling the complexities of cell migration - Many types of cell move towards substances they find attractive via a process called chemotaxis. In their latest Developmental Cell paper, Dr. Carole P...
In this video, Ira Espuny-Camacho and Pierre Vanderhaeghen describe how human pluripotent stem cells can be turned into cortical pyramidal neurons, mimicking key aspects of human corticogenesis. Most ...
Cell Surface Topography Is a Regulator of Molecular Interactions
A neutrophil labeled with Alexa-488-conjugated anti-L-selectin spreads onto and engulfs an IL-8-coated glass bead in bright field, epifluorescence, and TIRFM. See the paper by Lomakina et al. in the S...
Meiotic Nuclear Oscillations Are Necessary to Avoid Excessive Chromosome Associations. Pairing of homologous chromosomes is a crucial step in meiosis, which in fission yeast depends on nuclear oscilla...
Generation of complex behaviors by the brain requires the orchestrated activity of distinct neuronal populations. In this video, Javier Stern and Sook Jin Son describe their recent findings showing th...
Wnts come in small packages - Wnts are signaling molecules important for development and neuronal functions. Watch and listen as Vivian Budnik and her colleagues take you on a brief personally guided...
