Viruses Remodel Host Membranes to Promote Their Replication
Viruses Remodel Host Membranes to Promote Their Replication - Viruses know how to make themselves at home in host cells while rapidly proliferating. Watch and listen as Nihal Altan-Bonnet and colleag...
How to Undress an mRNP - Nonsense-mediated mRNA decay requires the RNA helicase Upf1, but as Jens Lykke-Andersen and colleagues explain, Upf1 does more than unwind RNA. It also strips off the mRNA's p...
Synapses are formed with high degree of specificity in our brain. In this VIDEO, Kang Shen and Kota Mizumoto describes "synaptic tiling" as a way to precisely organize the subcellular locati...
BRCA2 Bandages Stalled Forks - Maria Jasin and Katharina Schlacher reveal a new function for the breast cancer tumor suppressor BRCA2: in addition to repairing DNA damage, it prevents breaks from occu...
Cell-Type-Specific Sensorimotor Processing in the Striatum
Cell-Type-Specific Sensorimotor Processing in the Striatum - Carl Petersen describes whole-cell recordings from striatal projection neurons in behaving mice carried out by Tanya Sippy, and optogenetic...
What brain processes underlie memory consolidation? Here, scientists from the MRC BNDU (University of Oxford, UK) test the hypothesis that, in the mouse hippocampus, reactivation of space-representing...
Mengingitis Breaks the Blood-Brain Barrier. But how?
Mengingitis Breaks the Blood-Brain Barrier. But how? - Stefano Marullo and colleagues explain how meningococcus hijacks a beta-arrestin signaling cascade to open gaps and slip right through intercellu...
Thomas Südhof and colleagues reveal that neuroligin-3 mutations enhance repetitive behaviors similar to those seen in autism spectrum disorders by selectively affecting one type of medium spiny neuron...