Imaging Clock Oscillations in the Mouse Embryo

Imaging Clock Oscillations in the Mouse Embryo - The periodic, anteriorly traveling waves of cyclic gene expression can be seen in the presomitic mesoderm (PSM) of a transgenic mouse embryo. The trans...

Human Mutation - Tao Yang

Human Mutation - Tao Yang - YouTube...

A fovea for pain at the fingertips

How do we localize pain? Touch has an area of high spatial resolution, called a fovea, at the fingertips. In contrast, pain is considered to lack any equivalent to the tactile fovea on the fingertips....

KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation

Sadaf Farooqi and colleagues reveal how they sequenced more than 2,000 individuals with severe early onset obesity to identify mutations in the gene KSR2. They find that these mutations lead to impair...

How Endogenous Opioids Control Pain Sensitivity

How Endogenous Opioids Control Pain Sensitivity. A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins. Pain thresholds are, in part, set as a function of e...

Molecular Structure of β-Amyloid Fibrils in Alzheimer's Disease Brain Tissue

Robert Tycko and colleagues find that amyloid fibrils derived from AD patient brain tissue reveal a single predominant structure within a patient sample but with key differences between samples, raisi...

Bromine for Life

Hudson and colleagues shed light on ionic bromide, a micronutrient essential for animal life and its importance for the assembly of basement membranes and epithelial tissue development....

How chimpanzees handle death: Biro, part 1

How chimpanzees handle death: Biro, part 1 ...

2012 Three Minute Thesis Runner Up - Billie Ganendran

Billie Ganendran (Physical, Environmental & Mathematical Science, UNSW Canberra), runner-up in the 2012 UNSW Three Minute Thesis competition, gives her presentation - "The curious mix of peng...

TIM review on reverse zoonosis of influenza to swine

TIM review on reverse zoonosis of influenza to swine - YouTube...

Proton transport through a v ATPase proton channel

Proton transport through a v ATPase proton channel ...

Wnt signaling in Frontotemporal Dementia

Wnt signaling in Frontotemporal Dementia - Progranulin mutations cause frontotemporal dementia (FTD). In this video, Dan Geschwind and colleagues describe their analysis of the pathways downstream of ...

Genetic Interaction

An ERC research project led by Prof. Michael Boutros (DKFZ and Heidelberg University) analyzes genetic interactions in living cells with high-thoughput technology such as robotics and automatic micros...

Olfactory Signal Transformation

Olfactory Signal Transformation - How are incoming olfactory signals transformed into projection outputs in the olfactory bulb? Watch and listen as Jie Tan and Minmin Luo take you on a personally gui...

Keeping Gray Hairs at Bay, Wnt Coordinates Color with Growth

Keeping Gray Hairs at Bay, Wnt Coordinates Color with Growth - How does blonde hair stay blonde? Here, Ito and colleagues explain how Wnt signaling synchronizes two populations of stem cells in the ha...

Fish Biodiversity Loss in a High-CO2 World/ Curr. Biol., Jul. 6, 2017 (Vol. 27, Issue 14)

Fish Biodiversity Loss in a High-CO2 World. Nagelkerken et al. (University of Adelaide) show that ocean acidification can reduce fish biodiversity. This is due to the indirect effects of elevated CO2 ...

Sperm whales at rest

Sperm whales at rest ...

Spatially Addressable In Vivo Optogenetics with Multipoint-Emitting Optical Fibers

This video describes the implementation of a new optogenetic tool based on a single waveguide that, by a simple optical strategy, can selectively and dynamically illuminate multiple brain regions. F. ...

Chromosome congression during cell division

Chromosome congression during cell division ...

Fungal Biofilm in 3D

Fungal Biofilm in 3D ...