Not miRly a Knockout - Drs. Wang and Olson discuss their work on miR-129, as well as the general idea that gene loci encoding both a protein and an intronic microRNA commonly share regulated expressio...
DeCoN: High-Throughput Investigation of the Cortical Transcriptome
DeCoN: High-Throughput Investigation of the Cortical Transcriptome - Decoding the signals that shape and maintain the extraordinary neuronal diversity of the mammalian cortex remains a challenge. In t...
2012 Three Minute Thesis Runner Up - Billie Ganendran
Billie Ganendran (Physical, Environmental & Mathematical Science, UNSW Canberra), runner-up in the 2012 UNSW Three Minute Thesis competition, gives her presentation - "The curious mix of peng...
The asymmetrical clamp-loader pentamer (green, with pink ATP) spirals around a DNA double helix (yellow) and binds the sliding-clamp trimer (brown) around the DNA in an open lock-washer position....
Ocean 180 -- Innocence by Viral Tagging. Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in...
De Novo Coding Variants Are Strongly Associated With Tourette Disorder
De Novo Coding Variants Are Strongly Associated With Tourette Disorder. New research led by UC San Francisco scientists Jeremy Willsey and Matthew State has identified four likely risk genes with mult...
Assembly and budding of a virus from a membrane microdomain
Assembly and Budding of a Virus from a Membrane Microdomain - Viruses have an outer protein shell (called a capsid) that surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an addit...
With Age Comes Representational Wisdom in Social Signals
With Age Comes Representational Wisdom in Social Signals - Philippe Schyns and colleagues at the University of Glasgow explain how they used reverse correlation from noise to characterize mental repre...
Hierarchical Prediction Errors in Sensory Learning
Prediction errors (PEs) are crucial teaching signals for learning. Here, we show that different precision-weighted PEs map onto distinct neurotransmitter systems: the dopaminergic midbrain signals pre...
This video abstract accompanies the article The resilience of the forest field layer to anthropogenic disturbances depends on site productivity by Kaupo Kohv, Martin Zobel, Jaan Liira, published in Ca...
The Vertebrate Mitotic Checkpoint Protein BUBR1 Is an Unusual Pseudokinase. Chromosomal stability is safeguarded by a mitotic checkpoint, of which BUB1 and Mad3/BUBR1 are core components. These paral...