Yet Another Facet to Type I Interferon: Kiss of Death to Hepatocytes
Yet Another Facet to Type I Interferon: Kiss of Death to Hepatocytes - The liver is the target of many hepatitis viruses, which affect more than 500 million people worldwide and manifest with a comple...
Revitalizing Our View of Heart Development - Robert Kelly discusses the historical context for the work, outlines how research into the second heart field has progressed in the interim, and highlights...
Membranes Use Actin in a Pinch - Endocytosis requires invagination and scission of membranes. Watch and listen as Ludger Johannes and colleagues take you on a brief, personally guided tour of their f...
Connecting the Dots: Linking Sirtuins and AMPK in Metabolism and Aging
Connecting the Dots: Linking Sirtuins and AMPK in Metabolism and Aging - Vittorio Sartorelli and Marcella Fulco discuss their identification of a nutrient-sensing pathway that governs the differentiat...
Gain Control in Olfactory Circuits - All sensory systems must control the gain of incoming signals. Watch and listen as Rachel Wilson and colleagues take you on a personally guided tour of their study...
A New Strategy for Treating Neuropathic Pain - Conventional methods of pain treatment have often proved ineffective in the treatment of neuropathic pain. Here, in an effort to develop a new therapeuti...
Waking-like brain function in embryos - When in development do brains "wake up" for the first time? Balaban, Desco, and Vaquero (Current Biology, May 3, 2012) addressed this question using n...
Endogenous Nuclear RNAi Mediates Behavioral Adaptation to Odor
Noelle L'Etoile and colleagues describe an endogenous RNAi pathway that acts in neurons via a nuclear Argonaute and a heterochromatin protein to enable odor adaptation in C. elegans....
Parsing out blood stem cells - For many years, researcher thought that blood stem cells (HSCs) were a fairly uniform population. However, recent studies have started to show that this is not really t...
Reprogramming Exploits a Chink in Polycomb's Armor
Reprogramming Exploits a Chink in Polycomb's Armor - Could enhancers initiate reprogramming? Peter Jones explains how nucleasome-free zones provide a "landing strip" for master transcription...