Mengingitis Breaks the Blood-Brain Barrier. But how?
Mengingitis Breaks the Blood-Brain Barrier. But how? - Stefano Marullo and colleagues explain how meningococcus hijacks a beta-arrestin signaling cascade to open gaps and slip right through intercellu...
Neuronal Microcircuits Underlying Spatial Cognition - The functional microcircuits underlying spatial representations in medial entorhinal cortex (MEC) have not been described. Through their discovery...
Leptin nixes appetite through serotonin - Leptin is a molecule that acts in the brain to regulate appetite, energy expenditure and bone mass. Gerard Karsenty and his colleagues explain how they disco...
Exploring Astrocyte Diversity in Neural Circuits. Chai, Díaz-Castro et al. briefly highlight methods used to explore astrocytes in the hippocampus and striatum. The data show that astrocytes are disti...
Paving the Path for Nerve Regeneration - Peripheral nerves are able to regrow and regenerate following injury. Watch as Alison Lloyd and her colleagues take you on a brief, personally guided tour of t...
Caveolae Are Stress Sinks for Membranes - Latin for "little caves," caveolae are small folds in the plasma membrane associated with endocytosis.
Now Christophe Lamaze and colleagues outline...
Metformin and Neurogenesis with Freda Miller. Freda Miller and colleagues from The Hospital for Sick Children Research Institute give a guided tour of their work on metformin and neurogenesis, expandi...
Ken Cadwell and colleagues demonstrate that the bacterial sensor Nod2 prevents intestinal inflammation by regulating the intestinal microbiota, particularly the expansion of Bacteroides vulgatus, a co...
Lung cancer metastasis driven by WNT signaling - Cancer progresses in two stages: growth of a primary tumor followed by spreading of cancer cells to other tissues in the body, a process called metasta...
