Synaptic Tiling to Achieve Spatial Innervation

Synapses are formed with high degree of specificity in our brain. In this VIDEO, Kang Shen and Kota Mizumoto describes "synaptic tiling" as a way to precisely organize the subcellular location of synapses. The authors studied synaptic tiling using C. elegans motor neurons and found that the tiled synaptic innervation requires interaxonal communication and the Plexin/semaphorin signaling system.For more information,