Helicases Find Their Way - Hexameric helicases unwind DNA or RNA duplexes using ATP as an energy source. Watch and listen as James Berger and Nathan Thomsen take you on a brief, personally guided tou...
Time-Lapse Imaging of Retinal Pigment Epithelial Cells
Retinal pigment epithelial cells, labeled for vimentin (magenta) and microtubules (green), migrate through a 3D collagen matrix. See the article by Dean et a......
Cell-Type-Specific Sensorimotor Processing in the Striatum
Cell-Type-Specific Sensorimotor Processing in the Striatum - Carl Petersen describes whole-cell recordings from striatal projection neurons in behaving mice carried out by Tanya Sippy, and optogenetic...
When Genetic Instability Is a Good Thing - Dr. Orr-Weaver discusses her group's work on regulatory programs that amplify (or suppress) overreplication of cell-type-appropriate genes in the Drosophila ...
How Endogenous Opioids Control Pain Sensitivity. A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins. Pain thresholds are, in part, set as a function of e...
Randall Halfmann and colleagues question how budding yeast can acquire multicellular growth forms in response to their environment. The authors describe their work to show that the Mot3 transcription ...
Jean-Pierre Levraud, Nuno Palha, and Pierre Boudinot discuss how zebrafish can be used as a model for studying viral infections and host-virus interactions. For more information, see the related revie...
A Journey Into Entorhinal Cortex | Edvard and May-Britt Moser | NTNU
Kimberly Stroka and colleagues describe a propulsion mechanism for cancer cells that relies on a spatial gradient of channels and pumps in the plasma membrane, rather than acto-mysosin contractility....
In this video Drs. Samer Hattar and Tiffany Schmidt describe how light detection via the photopigment melanopsin in a conventional type of retinal gar1glion cell, the ON alpha cell, modulates contrast...