BRCA2 Bandages Stalled Forks - Maria Jasin and Katharina Schlacher reveal a new function for the breast cancer tumor suppressor BRCA2: in addition to repairing DNA damage, it prevents breaks from occu...
Snakes on the DNA Plane - How can protein complexes slide along DNA while still remaining wrapped up in its strands? Using optical tweezers and a baseball, Taekjip Ha and Ruobo Zhou show us how in thi...
Video Highlight: Author Aristea Binia on her recently published Human Mutation paper entitled "A Polymorphism Affecting MYB Binding Within the Promoter of th......
A nitrate sensor for plants - Sensing changes in soil ion concentration is essential for plants to survive and to sustain maximal growth. Ion sensors had not been identified in higher plants, but now ...
Lung cancer metastasis driven by WNT signaling - Cancer progresses in two stages: growth of a primary tumor followed by spreading of cancer cells to other tissues in the body, a process called metasta...
The Vertebrate Mitotic Checkpoint Protein BUBR1 Is an Unusual Pseudokinase. Chromosomal stability is safeguarded by a mitotic checkpoint, of which BUB1 and Mad3/BUBR1 are core components. These paral...