Research Discoveries in Schizophrenia - Meet the Scientists Webinar
Masseck et al. describe two new optogenetic tools to selectively activate the Gi/o pathway in anxiety circuitries. In the future these new tools might be applicable for new therapeutic strategies. For...
Leptin nixes appetite through serotonin - Leptin is a molecule that acts in the brain to regulate appetite, energy expenditure and bone mass. Gerard Karsenty and his colleagues explain how they disco...
When the Break Is Just around the Loop/ Cell, July 27, 2017 (Vol. 170, Issue 3)
When the Break Is Just around the Loop. Inside the nucleus, DNA is packed in highly complex structures that help to control which genes are on and off each time. In this video abstract, Andre Nussenzw...
Caveolae Are Stress Sinks for Membranes - Latin for "little caves," caveolae are small folds in the plasma membrane associated with endocytosis.
Now Christophe Lamaze and colleagues outline...
Myc and Multiple Myeloma: Drugging the Undruggable
Myc and Multiple Myeloma: Drugging the Undruggable - Reporting a new small-molecule inhibitor of chromatin-binding bromodomains, James Bradner and Constantine Mitsiades offer a back-door route to bloc...
Waking-like brain function in embryos - When in development do brains "wake up" for the first time? Balaban, Desco, and Vaquero (Current Biology, May 3, 2012) addressed this question using n...
Control of Cerebrovascular Networks Formation by Neural Activity
This video summarizes a study from Dr. Chenghua Gu's laboratory at Harvard Medical School, which demonstrates that sensory-related neural activity influences the formation of brain vascular networks d...
Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer
Richard Gregory and colleagues reveal that the Hippo-signaling pathway and its downstream target YAP regulate miRNA biogenesis in a cell-density-dependent manner, which may be responsible for the wide...
Video Abstract cjz-2014-0231 Negligible energetic cost of sonar jamming in a bat-moth interaction
This video abstract accompanies the article Negligible energetic cost of sonar jamming in a bat-moth interaction by Aaron J. Corcoran, H. Arthur Woods, published in Canadian Journal of Zoology. ...