In this video Drs. Samer Hattar and Tiffany Schmidt describe how light detection via the photopigment melanopsin in a conventional type of retinal gar1glion cell, the ON alpha cell, modulates contrast...
Figure360: Trends in Biotechnology, Johannssen and Lepenies, Figure 3
Glycan-Based Cell Targeting To Modulate Immune Responses. Glycosylation is an integral post-translational modification present in more than half of all eukaryotic proteins. It affects key protein func...
Feeding despite Immediate Metabolic Need - Christian Lüscher and Eoin O’Connor describe research that has investigated the role of inhibitory output from the nucleus accumbens shell to the lateral hyp...
Chromosome Loop—Cause or Consequence of Transcription
Chromosome Loop—Cause or Consequence of Transcription - Gerd Blobel and colleagues engineer a long-range genomnic interaction at the β-globin promoter to resolve this long-standing question....
Specified Neural Progenitors Sort to Form Sharp Domains after Noisy Shh Signaling
Sean Megason and colleagues determine how cells are sorted and spatially organized during development. The authors use live imaging in zebrafish to show that, despite variations in morphogen exposure ...
Circulating Hormones Control Gut Stem Cells in Diabetes
Circulating Hormones Control Gut Stem Cells in Diabetes - D’Addio et al. demonstrate that circulating IGF-I/IGFBP3 control human colonic stem cells and represent a therapeutic target for restoring col...