Song-Hai Shi explains how clonally related excitatory neurons in the hippocampus are progressively organized into discrete horizontal clusters and receive common synaptic inputs from nearby fast-spiki...
Awakening Stem Cells with Vitamins/Cell, May 4, 2017 (Vol. 169, Issue 5)
Awakening Stem Cells with Vitamins/Cell, (Vol. 169, Issue 5) . Billions of blood cells die every day and need to be replaced by new ones. In this video, Andreas Trumpp shows that Vitamin A is a key si...
Li et al. show that thalamocortical neurotransmission is required for the normal columnar, laminar, morphologic, and molecular-genetic development of sensory cortex....
Mantis shrimp tune their ultraviolet vision using biological sunscreens
Mantis shrimp tune the sensitivity of their ultraviolet photoreceptors using a unique application of filter pigments in the optical components in certain facets of their eyes. By combining four ultrav...
Waking-like brain function in embryos - When in development do brains "wake up" for the first time? Balaban, Desco, and Vaquero (Current Biology, May 3, 2012) addressed this question using n...
Obtaining a clear picture of the proteins that interact with the Huntingtin protein will provide clues for the development of Huntington's disease therapies. In this study, William Yang and colleagues...
Localized Axonal Translation in Retrograde Injury Signaling
Local translation in dendrites is known to have important physiological roles, but so far evidence is lacking for an essential role of mRNA localization in axons. In this study, Mike Fainzilber and co...
How do oil and other toxins move from deep water onto the beach? Using dye and drones, a team of scientists conduct a series of experiments to explore how ocean currents transport material from offsho...
Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport
Frédéric Saudou and colleagues explain why the glycolytic enzymes GAPDH and PGK are present on axonal vesicles: to provide a steady energy source that supplies the ATP necessary for fast axonal transp...
Shedding Light on HCN Channel Gating - The mechanism underlying HCN channel activation, including the relative contributions of membrane voltage and the ligand cAMP, is unknown. Klaus Benndorf and col...
Regional Sleep Oscillations in Humans - Slow waves and sleep spindles are the hallmarks of NREM sleep EEG. Watch and listen as Yuval Nir and colleagues take you on a guided tour of their findings demo...
Sonic Hedgehog Directs Cortical Circuit Formation - Sonic Hedgehog is one of the most widely studied molecules in developmental biology, with critical functions in tissue patterning, and proliferation...
Jeannie Lee and colleagues show that the X-linked Jpx noncoding RNA antagonizes the autosomally encoded CTCF transcription factor by titrating it away from the Xist promoter during X chromosome inacti...
Auditory Closed-Loop Stimulation of Sleep Slow Oscillations
Slow oscillations play a causal role in the consolidation of memory during sleep. In this video, Hong-Viet Ngo and Jan Born describe how they synchronized the presentation of auditory clicks to the br...
