The retrieval of previously formed memory triggers the lability of that memory for a short time and its reconsolidation. However, what exactly triggers memory reconsolidation is not known. Here, Diaz-...
How to Undress an mRNP - Nonsense-mediated mRNA decay requires the RNA helicase Upf1, but as Jens Lykke-Andersen and colleagues explain, Upf1 does more than unwind RNA. It also strips off the mRNA's p...
Circulating Hormones Control Gut Stem Cells in Diabetes
Circulating Hormones Control Gut Stem Cells in Diabetes - D’Addio et al. demonstrate that circulating IGF-I/IGFBP3 control human colonic stem cells and represent a therapeutic target for restoring col...
Social jetlag and its consequences. Why are most people in industrialized societies so tired? The reason lies in an increasing discrepancy between our body clocks' internal time and the social demands...
Cell-Type-Specific Sensorimotor Processing in the Striatum
Cell-Type-Specific Sensorimotor Processing in the Striatum - Carl Petersen describes whole-cell recordings from striatal projection neurons in behaving mice carried out by Tanya Sippy, and optogenetic...
We’ve all heard the expression “monkey see, monkey do", but actually, that's a myth. Imitation is very rare in the animal kingdom. Apes can imitate sometimes, but – apart from humans – the animal...
Endoderm Formation: Not So Black and White Anymore
Endoderm Formation: Not So Black and White Anymore - Dr. Hadjantonakis discusses the work of her group on using live-imaging approaches coupled with genetic labeling in the mouse embryo to uncover the...
TiBS Review Protein mistranslation: Friend or foe?
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The translation of genes into functional proteins is not error-free. Incorporation of the wrong amino acids, known as mistranslation, can cause disea...