A nitrate sensor for plants - Sensing changes in soil ion concentration is essential for plants to survive and to sustain maximal growth. Ion sensors had not been identified in higher plants, but now ...
Revitalizing Our View of Heart Development - Robert Kelly discusses the historical context for the work, outlines how research into the second heart field has progressed in the interim, and highlights...
Molecular Structure of β-Amyloid Fibrils in Alzheimer's Disease Brain Tissue
Robert Tycko and colleagues find that amyloid fibrils derived from AD patient brain tissue reveal a single predominant structure within a patient sample but with key differences between samples, raisi...
Building Stem Cell Niches from Scratch - Thomas Boehm and Lesly Calderón decode the rules of stem cell recruitment by reverse engineering the thymic niche....
Sonic Hedgehog Directs Cortical Circuit Formation - Sonic Hedgehog is one of the most widely studied molecules in developmental biology, with critical functions in tissue patterning, and proliferation...