D2 Receptor-DISC1 Complex and Antipsychotic Effects
D2 Receptor-DISC1 Complex and Antipsychotic Effects - Our lab has identified a novel interaction between D2 receptor and DISC1, and this complex was found to be increased in postmortem brain tissues o...
Friedhelm Hildebrandt describes how whole-exome resequencing of individuals with ciliopathies reveals mutations in DNA damage response genes, suggesting new pathogenic mechanisms behind this class of ...
Synaptic Pruning in the Developing Nervous System - Using light and serial electron microscopy, Jeff Lichtman and colleagues assessed the how axonal branching and synaptic connectivity change with dev...
Bidirectional Transcription and Antisense Repression of ataxin-7
Bidirectional Transcription and Antisense Repression of ataxin-7 - CAG repeat expansions in the ataxin-7 gene cause the neurodegenerative disorder SCA7. Al La Spada and colleagues have discovered tha...
Light, both natural and artificial, is a powerful cue for the circadian clock, the internal timing device that tells us when to wake up and go to sleep, when to eat, and when we are most mentally aler...
Neurexin-Neuroligin Function in Dendritogenesis - The cell adhesion molecules neurexin and neuroligin play a central role in synaptogenesis. In this video abstract, Kurt Haas and Simon Chen take you o...
Hudson and colleagues shed light on ionic bromide, a micronutrient essential for animal life and its importance for the assembly of basement membranes and epithelial tissue development....
Bubble templates in rats - While rodents are the first-choice animal model in the life sciences, they are rarely used as a model for higher visual functions. Here we report the performance of rats in ...
