Cascade Defense Tactics/Cell, Oct. 29, 2015 (Vol. 163, Issue 4) - CRISPR defends bacteria against viral invasion by recognizing the viral DNA sequence. What if virus mutates the sequence? The paper by...
Bidirectional Transcription and Antisense Repression of ataxin-7
Bidirectional Transcription and Antisense Repression of ataxin-7 - CAG repeat expansions in the ataxin-7 gene cause the neurodegenerative disorder SCA7. Al La Spada and colleagues have discovered tha...
Neocortex Recycles Olfactory Cajal-Retzius Cells - The neocortex undergoes extensive developmental growth, but how its architecture adapts to expansion remains largely unknown. Here, we investigated h...
Leaving Trash with Moms Keeps Daughters Young - In budding yeast, damaged and aggregated proteins segregate into the mother cell during cell division, leaving the newly budded daughter with a fresh st...
A Window into the Immune Landscape of Lung Cancer/Cell, May 4, 2017 (Vol. 169, Issue 4)
A Window into the Immune Landscape of Lung Cancer/Cell, (Vol. 169, Issue 4). mmunotherapy is revolutionizing treatment of patients with advanced cancer. But could it help patients with early stage tum...
Figure360: Trends in Biotechnology, Johannssen and Lepenies, Figure 3
Glycan-Based Cell Targeting To Modulate Immune Responses. Glycosylation is an integral post-translational modification present in more than half of all eukaryotic proteins. It affects key protein func...
Helicases Find Their Way - Hexameric helicases unwind DNA or RNA duplexes using ATP as an energy source. Watch and listen as James Berger and Nathan Thomsen take you on a brief, personally guided tou...
Figure360: Trends in Plant Science, Weber et al., Figure 1
Figure360: Trends in Plant Science, Weber et al., Higher eukaryotes typically contain many different cell types, displaying different cellular functions that are influenced by biotic and abiotic cues....
Cadherin Control of Dendrite Number - Dendrites vary widely in number and organization across types of neurons. Lisa Goodrich and colleagues investigate the mechanisms that define dendrite number in r...
What Makes an Osteoclast Special? - Hiroshi Takayanagi, discusses how he decided at the time to investigate the transcriptional effectors of osteoclast RANKL signaling, within Tadatsugu Taniguchi's gr...
Infant calming responses during maternal carrying in humans and mice
Mother-infant bonding is the earliest and most critical social relationship of mammalian infants, one that is promoted by an infant's innate desire to be close to his or her mother (as demonstrated by...
Engineering Microbiomes / Trends in Microbiology October 2015 (Vol. 23, Issue 10)
Engineering Microbiomes / Trends in Microbiology October 2015 (Vol. 23, Issue 10) - In this video and the accompanying review, Ulrich Mueller discusses how one might go about using host-mediated artif...
Human Owls, Larks, and Sports Performance - The circadian body clock plays an important role in the determination of performance in athletes. Human larks perform better earlier in the day, while human...
