Video Highlight: Author Aristea Binia on her recently published Human Mutation paper entitled "A Polymorphism Affecting MYB Binding Within the Promoter of th......
Li et al. show that thalamocortical neurotransmission is required for the normal columnar, laminar, morphologic, and molecular-genetic development of sensory cortex....
Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing
Eric Rubin and colleagues describe how tuberculosis bacteria undergo metabolic adaptation to survive attempts by CD4 T cells to starve them of tryptophan. They identify a small-molecule inhibitor of t...
Environmental Enrichment Rescues Precocious Critical Period
Critical periods are developmental time windows when neural circuits in the brain are shaped by experience. Jianhua Cang and colleagues show that a precocious critical period disrupts the matching of ...
Figure360: Trends in Cancer, Rozhok et al., Figure 2
Figure360: Trends in Cancer, Rozhok et al., The Armitage–Doll multistage model of carcinogenesis refocused cancer science by postulating that carcinogenesis is driven by a sequence of genetic changes ...
Extracellular Fuel for Metastasis - Cancer cells enhance their ability to metastasize by producing phospho-creatine, a metabolite that fuels metastatic survival, in the extracellular space. This proce...
Evolutionary Divergence in the Hedgehog Pathway - Drs. Toftgård, Teglund, and Heby-Henricson offer a personal account of the work published in this paper and highlight areas of current research on the...
This Neuron video abstract describes an experiment that used inactivation of the medial septal area to suppress the spatial firing patterns of grid cells to determine the role of grid cells in hippoca...
Microbial Invasions / Trends in Microbiology November 2015 (Vol. 23 Issue 11)
Microbial Invasions / Trends in Microbiology November 2015 (Vol. 23 Issue 11) - Cyrus Mallon and Joana Salles discuss how microbial invasions follow a universal process of introduction, establishment,...
Nematode escape from fungal traps - Predator-prey interactions shape the evolution of escape behaviors. Here, Mark Alkema and Chris Clark explain how the "model" nematode Caenorhabditis eleg...
Induced Neurons Recapitulate Cellular Phenotypes of an Autism Spectrum Disorder
Induced Neurons Recapitulate Cellular Phenotypes of an Autism Spectrum Disorder - Alysson Muotri and colleagues derive neurons from Rett patients' fibroblasts and then pharmacologically rescue defects...