Figure360: Trends in Biotechnology, Johannssen and Lepenies, Figure 3

Glycan-Based Cell Targeting To Modulate Immune Responses. Glycosylation is an integral post-translational modification present in more than half of all eukaryotic proteins. It affects key protein functions, including folding, stability, and immunogenicity. Glycoengineering approaches, such as the use of bacterial N-glycosylation systems, or expression systems, including yeasts, insect cells, and mammalian cells, have enabled access to defined and homogenous glycoproteins.