Cascade Defense Tactics/Cell, Oct. 29, 2015 (Vol. 163, Issue 4)

Cascade Defense Tactics/Cell, Oct. 29, 2015 (Vol. 163, Issue 4) - CRISPR defends bacteria against viral invasion by recognizing the viral DNA sequence. What if virus mutates the sequence? The paper by scientists from Eric Greene group of Columbia University and Jennifer Doudna group of UC Berkeley reveals a defense tactics used by bacterial Cascade complex to fight back.