Brain-wide pathway for waste clearance captured by contrast-enhanced MRI
Steven A. Goldman and Maiken Nedergaard at the University of Rochester Medical Center explain their findings in Cell Stem Cell, discussing how the human glia transplanted into mice positively affected...
New and Distinct Hippocampal Place Codes Are Generated Without Grid Cell Inputs
New and Distinct Hippocampal Place Codes Are Generated Without Grid Cell Inputs. This Neuron video abstract describes an experiment that used inactivation of the medial septal area to suppress the spa...
Depolarized Subicular Microcircuits in Epilepsy. The subiculum is crucially involved in spreading and generalizing hippocampal seizures. Wang et al. demonstrated depolarized GABAergic signaling caused...
Extracellular Fuel for Metastasis - Cancer cells enhance their ability to metastasize by producing phospho-creatine, a metabolite that fuels metastatic survival, in the extracellular space. This proce...
Deterministic preparation of superpositions of vacuum plus one photon by adaptive homodyne detection
Video abstract for the article ‘Deterministic preparation of superpositions of vacuum plus one photon by adaptive homodyne detection: experimental considerat......
Structural Insights into Competitive Antagonism in NMDA Receptors
Overactive N-methyl-D-aspartate (NMDA) receptors are implicated in several neurological disorders. However, mechanistic understanding of antagonism in NMDA receptors is limited due to a lack of antago...
Connecting Parkinson's Disease Gene Functions - This video describes the identification of functional interactions between Parkinson's disease genes VPS35, EIF4G1, and alpha-synuclein. Aaron Gitler an...
Neurons Tell the Vessels When to Grow - Yoshiaki Kubota and colleagues show how neurons in the retina titrate local VEGF levels and limit the growth of blood vessels to ensure an appropriate level of ...
Cues for Synapse Formation - The external cues that dictate synapse assembly are not well understood. Watch David Ginty and colleagues describe their findings that NGF plays a critical role in determi...
In this video Drs. Samer Hattar and Tiffany Schmidt describe how light detection via the photopigment melanopsin in a conventional type of retinal gar1glion cell, the ON alpha cell, modulates contrast...
Figure360: Trends in Biotechnology, Dunbar, Figure 5
Figure360: Trends in Biotechnology, Dunbar. Biotechnology could provide many innovative alternatives for changing the way metals are obtained. Microbes have been used to dissolve metallic minerals and...
Jean-Pierre Levraud, Nuno Palha, and Pierre Boudinot discuss how zebrafish can be used as a model for studying viral infections and host-virus interactions. For more information, see the related revie...
Polarity is destiny! - Cell polarity controls cell fate and is important for pancreas formation. Watch and listen as Henrik Semb and colleagues take you on a brief, personally guided tour of their fin...
Ocean 180 -- Innocence by Viral Tagging. Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in...
