The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation Ron Germain and colleagues identify the mitochondrial adapter molecule MAVS as a critical regulator of inflammasome activation. They discuss their findings on how MAVS and another adapter, ASC, are bo... Pancreatic Beta Cell Dedifferentiation as a Mechanism of Diabetic Beta Cell Failure Domenico Accili challenges a prevalent view that pancreatic Beta cells undergo apoptosis in conditions that induce diabetes, suggesting instead that dedifferentiation is a major mechanism of Beta cell... Created and maintained by Ryan Watkins (2013-present)
Biology
Biology