Parsing out blood stem cells - For many years, researcher thought that blood stem cells (HSCs) were a fairly uniform population. However, recent studies have started to show that this is not really t...
Argonaute Decoy Breaks the Silence - Argonaute proteins silence gene expression by binding small RNAs. Now, Xiuren Zhang and colleagues discover that AGO10 in plants achieves the opposite effect: it b...
PLANTS Review on Ambient temperature regulated flowering time
PLANTS Review on Ambient temperature regulated flowering time -- Created by Leonie Verhage, Gerco C. Angenent and Richard G.H. Immink (Wageningen University, The Netherlands). Read the related Review ...
Love? Oxytocin, Actually. Nathaniel Heintz and colleagues describe how a population of interneurons in the brain prefrontal cortex, responding to the hormone oxytocin, regulates females’ interest for ...
p53's Hit Men - p53 both activates and represses gene expression to defend against tumorigenesis. Watch and listen as John Rinn takes you on a brief, personally guided tour of his lab's findings that ...
Endocytosis Promotes Dendrite Growth - Cheng-Ting Chien and colleagues explore the mechanisms underlying dendrite extension in Drosophila and find that Nak, a clathrin adaptor-associated kinase, promo...
Hudson and colleagues shed light on ionic bromide, a micronutrient essential for animal life and its importance for the assembly of basement membranes and epithelial tissue development....
Revitalizing Our View of Heart Development - Robert Kelly discusses the historical context for the work, outlines how research into the second heart field has progressed in the interim, and highlights...
Network Organization of the Human Brain - In this study, Steven Petersen and co-authors present a preliminary draft of functional brain networks in healthy adults. With resting state fMRI, the authors...
Turning Ovaries into Testes - An ovary does not necessarily remain an ovary without all of the necessary genes at work, new work by Treier and colleagues shows. Watch and listen as Mathias Treier take...
Evolving Roles for Inhibitory Interneurons in Seizures
Evolving Roles for Inhibitory Interneurons in Seizures. Using a combination of optogenetics and calcium imaging, Khoshkhoo et al. show how various classes of interneurons play distinct and evolving ro...