Scattering of Cell Clusters in Confinement - Epithelial-to-mesenchymal transition (EMT) enables scattering of cell clusters and disseminates motile cells to distant locations in vivo during embryonic ...
Evolutionary Divergence in the Hedgehog Pathway - Drs. Toftgård, Teglund, and Heby-Henricson offer a personal account of the work published in this paper and highlight areas of current research on the...
Human Mutation - Yuehua Zhang, Liping Wei, and colleagues
Amplicon Resequencing Identified Parental Mosaicism for Approximately 10% of “de novo” SCN1A Mutations in Children with Dravet Syndrome. The majority of children with Dravet syndrome (DS) are caused b...
Untangling Chromosomes - Homologous chromosomes find each other and align correctly during meiosis with the help of the cytoskeleton, new work by Dernburg and colleagues shows. Watch and listen as Abb...
When Genetic Instability Is a Good Thing - Dr. Orr-Weaver discusses her group's work on regulatory programs that amplify (or suppress) overreplication of cell-type-appropriate genes in the Drosophila ...
External genital anatomy evolves rapidly and is remarkably diverse among animals that reproduce by internal fertilization. One of the most intriguing evolutionary transitions is the reduction and loss...
Imaging Clock Oscillations in the Mouse Embryo - The periodic, anteriorly traveling waves of cyclic gene expression can be seen in the presomitic mesoderm (PSM) of a transgenic mouse embryo. The trans...
