Helicases Find Their Way - Hexameric helicases unwind DNA or RNA duplexes using ATP as an energy source. Watch and listen as James Berger and Nathan Thomsen take you on a brief, personally guided tou...
Mengingitis Breaks the Blood-Brain Barrier. But how?
Mengingitis Breaks the Blood-Brain Barrier. But how? - Stefano Marullo and colleagues explain how meningococcus hijacks a beta-arrestin signaling cascade to open gaps and slip right through intercellu...
Blood-Brain Barrier Breakdown and Cognitive Impairment in Humans
Blood-Brain Barrier Breakdown and Cognitive Impairment in Humans - By imaging the living human brain, Montagne et al. show an age-dependent blood-brain barrier (BBB) breakdown in the hippocampus, a re...
Connecting the Dots: Linking Sirtuins and AMPK in Metabolism and Aging
Connecting the Dots: Linking Sirtuins and AMPK in Metabolism and Aging - Vittorio Sartorelli and Marcella Fulco discuss their identification of a nutrient-sensing pathway that governs the differentiat...
Dopamine: Motivation, Salience and Learning - A Genetic Perspective
Decision making is impacted by risk. Masaaki Ogawa and colleagues in the laboratory of Geoffrey Schoenbaum find that activity of risk-responsive neurons in the orbitofrontal cortex track salience bett...
Synapses are formed with high degree of specificity in our brain. In this VIDEO, Kang Shen and Kota Mizumoto describes "synaptic tiling" as a way to precisely organize the subcellular locati...
Hudson and colleagues shed light on ionic bromide, a micronutrient essential for animal life and its importance for the assembly of basement membranes and epithelial tissue development....
