Small neuronal Ensembles and Free Will

Small neuronal Ensembles and Free Will - Can the onset of free will in humans be predicted from the activity of small neuronal ensembles? By discovering that progressive neuronal activity begins befor...

Olfactory Signal Transformation

Olfactory Signal Transformation - How are incoming olfactory signals transformed into projection outputs in the olfactory bulb? Watch and listen as Jie Tan and Minmin Luo take you on a personally gui...

Walking-like neuronal circuits in a marine vertebrate

Walking-like neuronal circuits in a marine vertebrate - YouTube...

Extrinsic Cues in Neuronal Polarity

Extrinsic Cues in Neuronal Polarity - Is the site of axon emergence determined by intrinsic neuronal polarity or the local environment? Bill Harris and colleagues have found that laminin at the basal ...

Interaction of Serum-Exposed Microglial Cultures with pHrodo-Labeled Myelin Debris

Interaction of Serum-Exposed Microglial Cultures with pHrodo-Labeled Myelin Debris ...

Whole Brain Images of Thy1 Cre Retinal Ganglion Cell Axons

Whole Brain Images of Thy1 Cre Retinal Ganglion Cell Axons ...

Object Representations in Visual Agnosia

Object Representations in Visual Agnosia - How are visual and object representations affected by neural injury? In their study analyzing the re-organization of visual representations in an agnosic pat...

Fish Biodiversity Loss in a High-CO2 World/ Curr. Biol., Jul. 6, 2017 (Vol. 27, Issue 14)

Fish Biodiversity Loss in a High-CO2 World. Nagelkerken et al. (University of Adelaide) show that ocean acidification can reduce fish biodiversity. This is due to the indirect effects of elevated CO2 ...

Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

Florian Greten and colleagues explain why enhanced Wnt signaling causes postmitotic (non-stem) cells to dedifferentiate and reacquire stem cell characteristics, enabling the cells to initiate tumorige...

Figure360: Cell Chemical Biology, Gayvert et al., Figure 1

A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials. Over the past decade, the rate of drug attrition due to clinical trial failures has risen substantially. Unfortunately i...

Shedding Light on Hippocampus-Amygdala Communication

Shedding Light on Hippocampus-Amygdala Communication - Bazelot et al. dissect synaptic mechanisms orchestrating the information flow from the ventral hippocampus to the amygdala, two regions of the li...

Pancreatic Beta Cell Dedifferentiation as a Mechanism of Diabetic Beta Cell Failure

Domenico Accili challenges a prevalent view that pancreatic Beta cells undergo apoptosis in conditions that induce diabetes, suggesting instead that dedifferentiation is a major mechanism of Beta cell...

Single-Neuron Integration of Plasticity Mechanisms Actuates a Memory

Single-Neuron Integration of Plasticity Mechanisms Actuates a Memory - YouTube...

T. gondii Requires the Twisting Motion Driven by the RON Protein Complex

(3) T. gondii Requires the Twisting Motion Driven by the RON Protein Complex ...

Pongo tapanuliensis, a New Orangutan Species/ Curr. Biol., Nov. 2, 2017 (Vol. 27, Issue 22)

Pongo tapanuliensis, a New Orangutan Species/ Curr. Biol., Nov. 2, 2017 (Vol. 27, Issue 22) ...

D2 Receptor-DISC1 Complex and Antipsychotic Effects

D2 Receptor-DISC1 Complex and Antipsychotic Effects. Our lab has identified a novel interaction between D2 receptor and DISC1, and this complex was found to be increased in postmortem brain tissues o...

A Molecular View of Sperm Navigation

Clapham and colleagues describe a unique signaling mechanism in sperm flagella, in which a calcium channel organizes a signal transduction cascade in time and space, allowing sperm navigation toward t...

Onset and Sustained Maps in Human Speech Cortex/ Curr. Biol., May 31, 2018 (Vol. 28, Issue 12)

(1) Onset and Sustained Maps in Human Speech Cortex/ Curr. Biol., May 31, 2018 (Vol. 28, Issue 12) ...

Open-and-Shut Case for Ion Channels

Open-and-Shut Case for Ion Channels - K+ channels undergo conformational changes to switch conduction on and off. Watch and listen as Jacqui Gulbis and colleagues take you on a brief personalized tour...

Basolateral to Central Amygdala Neural Circuits for Appetitive Behaviors

Basolateral to Central Amygdala Neural Circuits for Appetitive Behaviors. In this study, Kim and Zhang et al. dissect a genetically defined circuit for appetitive behaviors from the basolateral amygda...