Induced Neurons Recapitulate Cellular Phenotypes of an Autism Spectrum Disorder
Induced Neurons Recapitulate Cellular Phenotypes of an Autism Spectrum Disorder - Alysson Muotri and colleagues derive neurons from Rett patients' fibroblasts and then pharmacologically rescue defects...
Developmental Cell Stumpff/Wordeman video abstract
Developmental Cell Stumpff/Wordeman - Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension. ...
Context- and Output Layer-Dependent Ensemble Plasticity in the OB
Context- and Output Layer-Dependent Ensemble Plasticity in the OB. Using chronic imaging in awake behaving mice, Yamada, Bhaukaurally et al. discovered two distinct forms of long-term ensemble plastic...
Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation
Jonathan Sebat and colleagues explain how they tested their hypothesis that hypermutability is a property of genes implicated in autism spectrum disorders (ASD). The authors used whole-genome sequenci...
Baillie Redfern - Video Abstract - Poster Presentation - Genomics: The Power and the Promise
Baillie Redfern, UBC, discusses her research "Engineering the production of isoprenoids from Abies balsamea in a biological host system" at the Genomics: The Power and The Promise (November ...
The clustering of regulatory elements within a gene desert provides an evolutionary palette for the development of fingers and toes, explains Denis Duboule....
TiBS Review Protein mistranslation: Friend or foe?
Read the full article here: http://bit.ly/1oGNRdF
The translation of genes into functional proteins is not error-free. Incorporation of the wrong amino acids, known as mistranslation, can cause disea...
Finding ESCRTs II and III - Markus Babst and David Katzmann talk about how the ESCRT project started and developed in the Emr lab, and where ESCRTs have gone from there....
