Central Control of Insect Locomotion - Insect locomotion, for example walking, depends on stereotypical movements that are generated locally by neural circuits - but, as John Bender and Roy Ritzmann e...
Coordinated Nose, Head, and Vibrissa Motion in Rats/ Curr. Biol., Feb. 16, 2017 (Vol. 27, Issue 5)
Coordinated Nose, Head, and Vibrissa Motion in Rats/ Curr. Biol., Kurnikova et al. examine orofacial movements in rats, which include nose orienting, head bobbing, and whisking. This video demonstrate...
Cindy Lee, on her published paper in Human Mutation entitled "Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks"...
Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation
Jonathan Sebat and colleagues explain how they tested their hypothesis that hypermutability is a property of genes implicated in autism spectrum disorders (ASD). The authors used whole-genome sequenci...
Li et al. show that thalamocortical neurotransmission is required for the normal columnar, laminar, morphologic, and molecular-genetic development of sensory cortex....
Ferroptosis: A New Type of Programmed Cell Death - Distinct from apoptosis, necrosis, and autophagy, "iron-dependent cell death" emerged while Brent Stockwell and his lab were investigating ...
Atomic Views of Viral Priming with Cryo-EM - Nonenveloped viruses must transform from a dormant state to a primed state for cell membrane penetration. Watch and listen as Hong Zhou takes you on a brie...
Cadherin Control of Dendrite Number - Dendrites vary widely in number and organization across types of neurons. Lisa Goodrich and colleagues investigate the mechanisms that define dendrite number in r...
Microbiome and Malaria - Miguel Soares describes how gut bacteria carrying a specific glycan residue can elicit antibodies in humans to an epitope found on malaria parasites and hence potentially conf...
Julie Blander and colleagues explain how MHC-I stored in the endosomal recycling compartment of dendritic cells is delivered to phagosomes for cross-presentation through TLR signaling-dependent mechan...
Flowers encourage pollinator visitation by producing nectar rewards, but there are also examples of deceptive flowers, such as many orchids, that provide nothing in return for pollination services. Th...
Sensing DNA Damage, ATP Orders an Mre11-Rad50 Clamp Down
Sensing DNA Damage, ATP Orders an Mre11-Rad50 Clamp Down - By trapping Mre11-Rad50 in mulitple states, Karl-Peter Hopfner and colleagues discover that Mre11-Rad50 transiently assembles into an ATP-con...
Bombing My Mind - The first author of the original Developmental Cell paper, Dr. Motoyuki Itoh, introduces the mind bomb mutation, the work he did on it in Dr. Ajay Chitnis's laboratory, and some unan...
