Evolution of Human Coronavirus Genomes

Evolution of Human Coronavirus Genomes/Trends in Microbiology - In this video and the accompanying review in Trends in Microbiology, Diego Forni, Rachele Cagliani, Mario Clerici, and Manuela Sironi discuss coronavirus genome evolution and how this affects its propensity for jumps between hosts. In particular, the high plasticity of coronavirus gene content allows for mutations especially in the spike protein that adapts to use receptors from different hosts.