A Simple Grammar Defines Activating and Repressing cis-Regulatory Elements in Photoreceptors. Transcription factors often activate and repress different target genes in the same cell. How activation a...
Molecular Structure of β-Amyloid Fibrils in Alzheimer's Disease Brain Tissue
Robert Tycko and colleagues find that amyloid fibrils derived from AD patient brain tissue reveal a single predominant structure within a patient sample but with key differences between samples, raisi...
Ocean 180 -- Bite Size: Bull Shark Predation of Tarpon. Predators can impact ecosystems through trophic cascades. Both bull sharks and tarpon are large predatory fish in tropical waters. They occupy s...
Sequential and Rhythmic Production of Somites - Illustrated with the developing zebrafish embryo, somitogenesis is a sequential and rhythmic process that subdivides the mesoderm of the vertebrate embr...
Personalized Nutrition/ Cell November 19, 2015 (Vol. 163, Issue 5)
Personalized Nutrition/ Cell November 19, 2015 (Vol. 163, Issue 5) - Doctors and nutrition specialists keep telling us what foods are good and bad for our metabolism and health. But does it work for e...
Turning Ovaries into Testes - An ovary does not necessarily remain an ovary without all of the necessary genes at work, new work by Treier and colleagues shows. Watch and listen as Mathias Treier take...
Li et al. show that thalamocortical neurotransmission is required for the normal columnar, laminar, morphologic, and molecular-genetic development of sensory cortex....
Figure360: Cell Chemical Biology, Gayvert et al., Figure 1
A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials. Over the past decade, the rate of drug attrition due to clinical trial failures has risen substantially. Unfortunately i...