Sortilin Link to Dementia Pathophysiology - Mutation of the gene for PGRN causes Fronto-Temporal Lobar Degeneration but the mechanistic link between reduced PRGN levels and neurodegeneration is unknow...
Rachel Dutton and colleagues describe how analysis of microbes residing on different types of cheese across the world can provide insight into microbial communities' assembly and function....
Neocortex Recycles Olfactory Cajal-Retzius Cells - The neocortex undergoes extensive developmental growth, but how its architecture adapts to expansion remains largely unknown. Here, we investigated h...
Combinatorial Genetic Targeting of GABAergic Neurons
Combinatorial Genetic Targeting of GABAergic Neurons - Article: Strategies and Tools for Combinatorial Targeting of GABAergic Neurons in Mouse Cerebral Cortex
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Mengingitis Breaks the Blood-Brain Barrier. But how?
Mengingitis Breaks the Blood-Brain Barrier. But how? - Stefano Marullo and colleagues explain how meningococcus hijacks a beta-arrestin signaling cascade to open gaps and slip right through intercellu...
Membranes Use Actin in a Pinch - Endocytosis requires invagination and scission of membranes. Watch and listen as Ludger Johannes and colleagues take you on a brief, personally guided tour of their f...
How Attenuated Viruses Become Virulent / Cell, March 23, 2017 (Vol. 169, Issue 1)
How Attenuated Viruses Become Virulent. In this issue’s Video Abstract, Raul Andino describes the evolutionary strategies by which vaccine strains can become pathogenic, and provides a framework for r...