Exploring Astrocyte Diversity in Neural Circuits. Chai, Díaz-Castro et al. briefly highlight methods used to explore astrocytes in the hippocampus and striatum. The data show that astrocytes are disti...
Ken Cadwell and colleagues demonstrate that the bacterial sensor Nod2 prevents intestinal inflammation by regulating the intestinal microbiota, particularly the expansion of Bacteroides vulgatus, a co...
Julie Blander and colleagues explain how MHC-I stored in the endosomal recycling compartment of dendritic cells is delivered to phagosomes for cross-presentation through TLR signaling-dependent mechan...
The function of hippocampal area CA2 has remained unclear for over 75 years. Watch and listen as Steve Siegelbaum and Vivien Chevaleyre take you on a persona......
Memory Enhancement by Targeting NR2B Cell Surface Regulation
Many neurological disorders, such as Alzheimer's disease, are characterized by learning and memory deficits, for which cognitive enhancement is considered a valid treatment strategy. Plattner and coll...
Combinatorial Genetic Targeting of GABAergic Neurons
Combinatorial Genetic Targeting of GABAergic Neurons - Article: Strategies and Tools for Combinatorial Targeting of GABAergic Neurons in Mouse Cerebral Cortex
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PINK1/Parkin Derails Damaged Mitochondria -Thomas Schwarz shows how Parkinson's disease proteins quarantine damaged mitochondria by disconnecting them from the microtubule network....
This video provides a short introduction to human brain oscillations and demonstrates how transcranial stimulation can be used for a controlled manipulation of the timing of brain oscillations to then...
Cancers Chew the Fat - Tumors undergo metabolic changes associated with increased malignancy. Watch and listen as Ben Cravatt and colleagues take you on a personally guided tour of their findings that...
The scent of danger: A 70-year-old puzzle solved - When injured, many freshwater fish release an alarm substance that triggers fear in other members of their school. This substance, which is found in ...
Cell-Type-Specific Sensorimotor Processing in the Striatum
Cell-Type-Specific Sensorimotor Processing in the Striatum - Carl Petersen describes whole-cell recordings from striatal projection neurons in behaving mice carried out by Tanya Sippy, and optogenetic...
Intact Mirror Neuron Function in Autism - It has been proposed that dysfunction of the mirror neuron system may underlie the social difficulties associated with autism. Watch and listen as Ilan Dinste...