Drosophila CNS Glutamate Receptors Break the Rules

Using structural and electrophysiological techniques Li, Dharkar et al. find that Drosophila CNS glutamate receptors have unexpected ligand selectivity. The kainate receptor DKaiR1D is inhibited by NMDA and AP5, while DGluR1 is weakly activated by its namesake agonist AMPA.