Control of Cerebrovascular Networks Formation by Neural Activity
This video summarizes a study from Dr. Chenghua Gu's laboratory at Harvard Medical School, which demonstrates that sensory-related neural activity influences the formation of brain vascular networks d...
POMC Neuron Heterogeneity - POMC neurons of hypothalamic arcuate nucleus regulate food intake, energy homeostasis and glucose metabolism. Joel Elmquist and colleagues describe their new work that prov...
Human Mutation - Kakkhee Yeung "Transdifferentiation of Human Dermal Fibroblasts to Smooth Muscle-Like Cells to Study the Effect of MYH11 and ACTA2 Mutations in Aortic Aneurysms"...
PLANTS Review on The node, a hub for mineral nutrient distribution
PLANTS Review on The node, a hub for mineral nutrient distribution -- Created by Naoki Yamaji and Jian Feng Ma (Okayama University, Japan). Read the related Review in Trends in Plant Science here http...
Martha Giraldo, a research associate in the Department of Plant Pathology, was recently recognized for her innovative use of electronic media in her doctoral dissertation. She is one of three recipien...
How are distinct action and object categories represented in the human brain? Alexander Huth, Jack Gallant, and colleagues examined the representation of 1,705 object and action categories in the huma...
Richard Lee, Amy Wagers, and colleagues describe their parabiosis experiments in mice, which helped unravel a role for the TGF-beta family member GDF-11 as a negative regulator of age-associated cardi...
Mutations in GlialCAM Can Cause the Leukodystrophy MLC
Mutations in GlialCAM Can Cause the Leukodystrophy MLC - Mutations in the cell adhesion molecule GlialCAM can cause the leukodystrophy MLC. Raul Estevez and colleagues find that GlialCAM acts as an au...
Andy Dillin and colleagues show that, in the nematode worm C. elegans, activation of the unfolded protein response (UPR) regulator XBP-1 in neurons produces a signal that stimulates UPR in intestinal ...
Orbitofrontal Cortex: Prediction and Evaluation of Behavioral Outcomes
Orbitofrontal Cortex: Prediction and Evaluation of Behavioral Outcomes - The orbitofrontal cortex has long been associated with concepts like impulsivity, self-control, and emotion regulation. Here we...
p53's Hit Men - p53 both activates and represses gene expression to defend against tumorigenesis. Watch and listen as John Rinn takes you on a brief, personally guided tour of his lab's findings that ...
CRISPR-Cas9 has been repurposed to precisely edit the genome. In this video and the Cell paper published in the December 15 issue of Cell, Alan Davidson's group at the University of Toronto and Erik S...
PLANTS Opinion Ecological understanding of root-infecting fungi
Created by Matthias C. Rillig and colleagues and featuring Carlos A. Aguilar-Trigueros. Read the related Review in the July 2014 issue of Trends in Plant Science at http://bit.ly/1er9cSK...
In this video, Ira Espuny-Camacho and Pierre Vanderhaeghen describe how human pluripotent stem cells can be turned into cortical pyramidal neurons, mimicking key aspects of human corticogenesis. Most ...
Bombing My Mind - The first author of the original Developmental Cell paper, Dr. Motoyuki Itoh, introduces the mind bomb mutation, the work he did on it in Dr. Ajay Chitnis's laboratory, and some unan...