Thalamic Mechanism of Parkinson Disease. Hyper-inhibition of thalamic neurons by the basal ganglia inputs has been proposed as a mechanism for Parkinson's disease. This study shows that rebound firing...
Viruses Remodel Host Membranes to Promote Their Replication
Viruses Remodel Host Membranes to Promote Their Replication - Viruses know how to make themselves at home in host cells while rapidly proliferating. Watch and listen as Nihal Altan-Bonnet and colleag...
Risky Decisions: A Role for Rostrolateral PFC - How do we decide between the familiar and the unknown? David Badre, Michael Frank, and colleagues find that the pattern of neural activity in rostrolate...
The architecture of adaptation - Cells and organisms need to respond to external stimuli, but then reset, in a process called adaptation, so they can be prepared to respond to further perturbations. ...
How do we localize pain? Touch has an area of high spatial resolution, called a fovea, at the fingertips. In contrast, pain is considered to lack any equivalent to the tactile fovea on the fingertips....
Smart T Cell Vaccines: CAR T Cells - by Carl June, MD
Erika Pearce and colleagues challenge previous ideas about T cell metabolism by showing that activated T cells switch from oxidative phosphorylation to aerobic glycolysis not to promote proliferation ...
Why Scratching an Itch Makes You Itch More - Dr. Zhou-Feng Chen’s team explains why scratching make you itch more. You scratch an itch to cause minor pain, which prompts the brain to release serotonin...
