A New Way to Make Induced Pluripotent Stem Cells - Dr. Edward Morrisey at the University of Pennsylvania's Department of Medicine reports on a new way to make induced pluripotent stem cells with miRNA...
Turning Ovaries into Testes - An ovary does not necessarily remain an ovary without all of the necessary genes at work, new work by Treier and colleagues shows. Watch and listen as Mathias Treier take...
Orbitofrontal Cortex: Prediction and Evaluation of Behavioral Outcomes
Orbitofrontal Cortex: Prediction and Evaluation of Behavioral Outcomes - The orbitofrontal cortex has long been associated with concepts like impulsivity, self-control, and emotion regulation. Here we...
In this video, Drs. Christopher Cowan and Laura Smith describe how the protein that is missing in Fragile X syndrome, FMRP, normally controls behavioral and synaptic responses to cocaine exposure. Wit...
De Novo Coding Variants Are Strongly Associated With Tourette Disorder
De Novo Coding Variants Are Strongly Associated With Tourette Disorder. New research led by UC San Francisco scientists Jeremy Willsey and Matthew State has identified four likely risk genes with mult...
Sequential and Rhythmic Production of Somites - Illustrated with the developing zebrafish embryo, somitogenesis is a sequential and rhythmic process that subdivides the mesoderm of the vertebrate embr...
Human Mutation - Yuehua Zhang, Liping Wei, and colleagues
Amplicon Resequencing Identified Parental Mosaicism for Approximately 10% of “de novo” SCN1A Mutations in Children with Dravet Syndrome. The majority of children with Dravet syndrome (DS) are caused b...