Lung cancer metastasis driven by WNT signaling

Lung cancer metastasis driven by WNT signaling - Cancer progresses in two stages: growth of a primary tumor followed by spreading of cancer cells to other tissues in the body, a process called metastasis. Metastasis renders cancers more difficult to treat and thus learning how it is regulated is a key goal of cancer research. Dr. Joan Massague and his colleagues show that activation of the WNT signaling pathway regulates the ability of lung tumor cells to spread to the bone and brain.