Long-Term Synaptic Depression Triggered by Microglia

Zhang et al. discovered that microglial cells sense inflammatory stimuli and hypoxia in the brain via complement receptor 3 and produce reactive oxygen species (ROS) by NADPH oxidase. The diffusion of...

Complexity of Sexual Deception Uncovered/ Curr. Biol., Jun. 15, 2017 (Vol. 27, Issue 13)

Complexity of Sexual Deception Uncovered/ Curr. Biol., Jun. 15, 2017 (Vol. 27, Issue 13) ...

Pancreatic Beta Cell Dedifferentiation as a Mechanism of Diabetic Beta Cell Failure

Domenico Accili challenges a prevalent view that pancreatic Beta cells undergo apoptosis in conditions that induce diabetes, suggesting instead that dedifferentiation is a major mechanism of Beta cell...

PLANTS Opinon on Effector-triggered defence against apoplastic fungal pathogens

Effector-triggered defence against apoplastic fungal pathogens - Created by Bruce D.L. Fitt and colleagues (University of Hertfordshire). Read the related Opinion article in Trends in Plant Science he...

Induced Neurons Recapitulate Cellular Phenotypes of an Autism Spectrum Disorder

Induced Neurons Recapitulate Cellular Phenotypes of an Autism Spectrum Disorder - Alysson Muotri and colleagues derive neurons from Rett patients' fibroblasts and then pharmacologically rescue defects...

Pessimism in honeybees

Pessimism in honeybees - Do invertebrates-- presumed not to have emotions-- exhibit pessimism like depressed people? Melissa Bateson and Geraldine Wright explain new research showing that honeybees be...

A 360° View of Deep in the Cerebral Cortex

A 360° View of Deep in the Cerebral Cortex...

Amygdala Predicts Stress Vulnerability

Amygdala Predicts Stress Vulnerability - This video summarizes the results of a Duke University study finding that higher amygdala reactivity to threat predicts greater symptoms of anxiety and depress...

Signal Use by Octopuses in Agonistic Interactions/ Curr. Biol., Jan. 28, 2016 (Vol. 26, Issue 3)

Signal Use by Octopuses in Agonistic Interactions/ Curr. Biol., Jan. 28, 2016 (Vol. 26, Issue 3) - YouTube...

Engineering Microbiomes / Trends in Microbiology October 2015 (Vol. 23, Issue 10)

Engineering Microbiomes / Trends in Microbiology October 2015 (Vol. 23, Issue 10) - In this video and the accompanying review, Ulrich Mueller discusses how one might go about using host-mediated artif...

Natural Off-Switch of Cas9/Cell, Dec. 8, 2016 (Vol. 167, Issue 7)

CRISPR-Cas9 has been repurposed to precisely edit the genome. In this video and the Cell paper published in the December 15 issue of Cell, Alan Davidson's group at the University of Toronto and Erik S...

Fluoroquinolone resistance in bacteria

Liam Redgrave, Sam Sutton, Mark Webber, and Laura Piddock discuss bacterial resistance to fluoroquinolones. They explore how fluoroquinolones target bacterial type II topoisomerases to interfere with ...

New and Distinct Hippocampal Place Codes Are Generated Without Grid Cell Inputs

New and Distinct Hippocampal Place Codes Are Generated Without Grid Cell Inputs. This Neuron video abstract describes an experiment that used inactivation of the medial septal area to suppress the spa...

Egg Roll

Egg Roll ...

Human Mutation - Bodour Salhia

Human Mutation - Bodour Salhia - YouTube...

How Tuberculosis Begins

How Tuberculosis Begins ...

V2 in Motion Perception

V2 in Motion Perception - Motion perception is thought to be mediated by the dorsal visual pathways. In this video abstract, Anna Roe and colleagues discuss their data demonstrating that V2 is also in...

Flying through the Alzheimer's brain

Flying through the Alzheimer's brain ...

Reconstruction of the 50S Ribosome from the Initial Random Model to the Final Model

Reconstruction of the 50S Ribosome from the Initial Random Model to the Final Model - YouTube...

Mitochondrial links to genomic instability in aging

Mitochondrial links to genomic instability in aging - Understanding why our genomes become more prone to mutations as we age is a key goal of ageing and cancer research. Dr. Dan Gottschling and his co...