Phospholipid Enters Receptor's G-Protein Binding Site

Phospholipid Enters Receptor's G-Protein Binding Site - A phospholipid from the membrane's cytosolic leaflet (yellow) enters the empty G-protein binding site of an activated beta 2 adrenergic receptor and forms salt-bridge interactions that inhibit ionic lock formation and prolong active-state residency in a 14 µs atomistic molecular dynamics simulation