Restoring Study 329: efficacy and harms of paroxetine in adolescents Restoring Study 329: efficacy and harms of paroxetine in adolescents - Jon Jueridini and colleagues have reanalysed SmithKline Beecham’ infamous Study 329 (published by Keller and colleagues in 2001), the primary objective of which was to compare the efficacy and safety of paroxetine and imipramine with placebo in the treatment of adolescents with unipolar major depression. The reanalysis under the restoring invisible and abandoned trials (RIAT) initiative was done to see whether access to and
Contributed by: Susan Chan
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