DeCoN: High-Throughput Investigation of the Cortical Transcriptome

DeCoN: High-Throughput Investigation of the Cortical Transcriptome - Decoding the signals that shape and maintain the extraordinary neuronal diversity of the mammalian cortex remains a challenge. In this video abstract, Molyneaux, Goff, and colleagues present a broadly applicable approach combining antibody-based purification of individual neuronal subtypes together with massively parallel RNA sequencing to resolve the transcriptome of pyramidal neuron populations during development.