miRNA Decoy in Tumor Suppression

miRNA Decoy in Tumor Suppression - miRNAs are known to downregulate target mRNAs by complementary base pairing, but there's more to the story. Watch and listen as Danilo Perrotti and Anna Eiring take you on a brief, personalized tour of their discovery that miRNAs also act as decoys, boosting gene expression by binding and inhibiting hnRNPs involved in translational repression. The decoy function of miR-382 plays an important role in suppressing leukemia progenitors.