Avoiding Ribosome Traffic Jams

Avoiding Ribosome Traffic Jams - Optimization of protein synthesis for efficiency is thought to be highly important for evolutionary fitness. Watch and listen as Yitzhak Pilpel and Tamir Tuller take you on a brief, personalized tour of their findings that mRNA codons are distributed along the length of the message in a manner that modulates ribosome speed during translation. The ribosome "traffic pattern" generated by conserved codon distribution might minimize cellular energy expendit

Contributed by: David Simmons

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