Imaging Clock Oscillations in the Mouse Embryo

Imaging Clock Oscillations in the Mouse Embryo - The periodic, anteriorly traveling waves of cyclic gene expression can be seen in the presomitic mesoderm (PSM) of a transgenic mouse embryo. The transgene expresses a destabilized YFP from the cyclic promoter of the Lunatic Fringe gene, an oscillating component of the mouse segmentation clock. See Aulehla et al., 2008. Nat Cell Biol. 10(2):186-93 for more details.