Rethinking Embryonic Germ Layers

Rethinking Embryonic Germ Layers - Elena Tzouanacou and Val Wilson discuss their interests in mammalian cell lineages and how they came to identify one such lineage that violates a strict assumption of germ-layer segregation, as described in their Developmental Cell paper. They also mention recent work that suggests how the behavior of this cell lineage may be regulated to give rise to both mesodermal and neural cell types.