How Does the Brain Navigate in Space

This Neuron video abstract describes an experiment that used inactivation of the medial septal area to suppress the spatial firing patterns of grid cells to determine the role of grid cells in hippocampal place coding. The results of this study suggest that spatial inputs from grid cells are not required for hippocampal place cells to form a distinct spatial representation of a new environment. For more information, see Brandon et al., Neuron 82(4).