Spatially Addressable In Vivo Optogenetics with Multipoint-Emitting Optical Fibers

This video describes the implementation of a new optogenetic tool based on a single waveguide that, by a simple optical strategy, can selectively and dynamically illuminate multiple brain regions. F. Pisanello et al. exploited this easy to use and minimally invasive device to demonstrate the specific activation and function of GABAergic interneurons in different layers of cerebral cortex, as well as the selective