In Vivo Imaging of Neuron and Glial Cell Activity with a New GCaMP5 Reporter Mouse

In this video abstract, we present a new Cre-dependent GCaMP5G reporter mouse (PC::G5-tdT) targeted the PolR2a locus. We demonstrate the utility of this mouse line for imaging calcium activity in neurons, astrocytes and microglia. For more information, see Gee et al., Neuron 83(5),