Effect of melatonin on nocturnal blood pressure - Video abstract: 24603

Effect of melatonin on nocturnal blood pressure: meta-analysis of randomized controlled trials. Add-on controlled-release melatonin to antihypertensive therapy is effective and safe in ameliorating nocturnal hypertension, whereas fast-release melatonin is ineffective. It is necessary that larger trials of longer duration be conducted in order to determine the long-term beneficial effects of controlled-release melatonin in patients with nocturnal hypertension.