Tumor-specific formation of enzyme instructed supramolecular self-assemblies as cancer theranostics

Tumor-specific formation of enzyme instructed supramolecular self-assemblies as cancer theranostics - Despite the effort of developing various nanodelivery systems, most of them suffer from undesired high uptakes by the reticuloendothelial system, such as liver and spleen. Herein we develop an endogenous phosphatase-triggered coassembly strategy to form tumor-specific indocyanine green (ICG)-doped nanofibers (5) for cancer theranostics.